DoseGuidelines

Site Procedure Radiopharmaceutical Dose by Weight Adult (70kg) Minimum Maximum
Bone Whole body Tc-99m MDP 0.360 mCi/kg 25 mCi 3 mCi
Bone Limited & 3-Phase Tc-99m MDP 0.360 mCi/kg 25 mCi 3 mCi 32 mCi
Bone 3-Phase Bone PEDS (planar) Tc-99m MDP 0.360 mCi/kg 25 mCi 1 mCi
Bone 3-Phase Bone PEDS (SPECT) Tc-99m MDP 0.360 mCi/kg 25 mCi 2 mCi  
Bone SPECT Tc-99m MDP 0.360 mCi/kg 25 mCi 3 mCi
Bone Bone Marrow Tc-99m Sulfur Colloid 0.143 m Ci/kg 10 mCi 0.500 mCi  
Brain Perfusion Tc-99m Neurolite (Bicisate ECD) 0.430 mCi/kg 30 mCi 5 mCi
Brain Perfusion Tc-99m Ceretec (HMPAO) 0.430 mCi/kg 30 mCi 5 mCi  
Brain Brain Death Tc-99m Neurolite (Bicisate ECD) 0.430 mCi/kg 30 mCi 5 mCi
Brain Brain Death Tc-99m Ceretec (HMPAO) 0.430 mCi/kg 30 mCi 5 mCi  
Brain Tumor Tl-201 Thallium 0.057 mCi/kg 4 mCi 5 mCi
Brain Tumor Tc-99m Sestamibi 0.357 mCi/kg 25 mCi 5 mCi  
Cardiac Myocardial REST Tc-99m Sestamibi/Tetrafosmin 0.114 mCi/kg 8 mCi 8 mCi 15 mCi
Cardiac Myocardial STRESS Tc-99m Sestamibi/Tetrafosmin 0.357 mCi/kg 25 mCi 25 mCi 45 mCi
Cardiac Myocardial REST Tl-201 Thallium 0.043 mCi/kg 3 mCi
Cardiac Myocardial STRESS Tl-201 Thallium 0.043 mCi/kg 3 mCi    
Cardiac Myocardial Redistribution Tl-201 Thallium 0.043 mCi/kg 3 mCi
Cardiac Reinjection Tl-201 Thallium 0.014 mCi/kg 1 mCi    
Cardiac Myocardial Infarct Imaging Tc-99m Pyrophosphates 0.285 mCi/kg 20 mCi
Cardiac MUGA Tc-99m RBC 0.285 mCi/kg 30 mCi 5 mCi 30 mCi
CNS Cisternogram In-111 DTPA 0.007 mCi/kg 0.500 mCi 0.200 mCi
CNS CSF Leak In-111 DTPA 0.007 mCi/kg 0.500 mCi 0.200 mCi  
CNS Shunt Studies (VP & LP) In-111 DTPA 0.007 mCi/kg 0.500 mCi 0.200 mCi
Endocrine Adrenal I-131 Iodocholesterol (NP-59) 0.014 mCi/kg 1.0 mCi    
Endocrine Kidney Localizer Tc-99m DTPA or MAG 3 0.500 mCi
Endocrine Parathyroid Tc-99m Sestamibi   22 mCi    
Endocrine Parathyroid/Dual Tc-99m & Tl-201 2 mCi each
Endocrine Thyroid Uptake & Scan I-123 Sodium iodide cap (PO)   0.200 mCi 0.050-0.10 mCi  
Endocrine Thyroid Uptake & Scan Tc-99m 6 mCi
Endocrine Thyroid Uptake only I-123 Sodium iodide cap (PO)   0.200 mCi 0.050-0.10 mCi  
Endocrine Total Body Scan (low iodine diet) I-131 Sodium iodide (PO) 3 mCi
Endocrine Total Body Scan (with rhTSH) I-131 Sodium iodide (PO) 4 mCi
Endocrine Total Body Scan I-123 Sodium iodide (PO)   1.5 mCi    
Endocrine Therapeutic (Rx) I-131 (Dose determined by MD) 5-200 mCi
Gastrointestinal Liver-Spleen (SPECT) Tc-99m Sulfur Colloid 0.090 mCi/kg 6 mCi 0.500 mCi  
Gastrointestinal Liver-Spleen (Planar) Tc-99m Sulfur Colloid 0.090 mCi/kg 6 mCi 0.500 mCi
Gastrointestinal RBC Liver Tc-99m RBC 0.290 mCi/kg 20 mCi 3 mCi  
Gastrointestinal HIDA, Standard Tc-99m HIDA (Choletech) 0.100 mCi/kg 5 mCi 2 mCi
Gastrointestinal HIDA, Transplant Tc-99m HIDA (Choletech) 0.100 mCi/kg 5 mCi 2 mCi  
Gastrointestinal HIDA, Dynamic Tc-99m HIDA (Choletech) 0.100 mCi/kg 5 mCi 2 mCi
Gastrointestinal Gastric Emptying Tc-99m Sulfur Colloid 0.0143 mCi/kg 1 mCi 0.250-1.0 mCi  
Gastrointestinal GI Bleed Tc-99m RBC 0.285 mCi/kg 20 mCi 3 mCi
Gastrointestinal GI Bleed Tc-99m Sulfur Colloid   6 mCi    
Gastrointestinal Meckels Diverticulum Tc-99m Pertechnetate 0.142 mCi/kg 10 mCi 1 mCi
Gastrointestinal Intrahepatic Pump Patency Tc-99m MAA (infra-pump)   3 mCi    
Gastrointestinal Leveen/Denver Shunt Tc-99m MAA (intraperitoneal) 4 mCi 0.050 mCi
Hematology Plasma Volume I-125 albumin   0.005-0.010 mCi    
Hematology Red Cell Mass Cr-51 RBC (Sodium Chromate) 0.002 mCi/kg 0.150 mCi
Hematology Red Blood Cell Survival Cr-51 (Sodium Chromate)   0.150 mCi    
Infection Abdominal/Extremities In-111 Oxine labeled WBC 0.007 mCi/kg 0.500 mCi 0.050 mCi
Infection Abdominal/Extremities Tc-99m HMPAO labeled WBC 0.268 mCi/kg 20 mCi    
Infection Abdominal/Extremities Ga-67 Gallium Citrate 0.090 mCi/kg 6 mCi 1 mCi
Infection Lung Ga-67 Gallium Citrate 0.090 mCi/kg 6 mCi 1 mCi  
Lung Perfusion (V/Q) Tc-99m MAA 0.017 mCi/kg 1.5 mCi 0.200 mCi
Lung Ventilation (V/Q) Tc-99m DTPA (aerolized) 6 mCi 1 mCi
Lung Perfusion (V/Q) Tc-99m MAA   5 mCi    
Lung Ventilation (V/Q) Xe-133   10 mCi    
Lung Quantitative Tc-99m MAA 0.017 mCi/kg 1.5 mCi 0.200 mCi
Lung Right to left Shunt Tc-99m MAA 0.017 mCi/kg 1.2 mCi 0.200 mCi  
Renal Standard & Transplant Tc-99m MAG 3 0.142 mCi/kg 10 mCi 3 mCi
Renal Standard & Transplant Tc-99m DTPA 0.142 mCi/kg 10 mCi 3 mCi  
Renal Static Renal (Parenchymal) Tc-99m DMSA 0.029 mCi/kg 2 mCi 0.500 mCi
Renal Testicular Tc-99m Pertechnetate 0.290 mCi/kg 20 mCi 5 mCi  
Renal VCUG Tc-99m DTPA 0.140 mCi/kg I mCi
Renal GFR I-125 Sodium Iothalamate (Glofil)   0.03 mCi    
Renal GFR Tc-99m DTPA 0.014 mCi/kg 1.000 mCi 0.100 mCi
Renal GFR In-111 DTPA 0.003 mCi/kg      
Therapeutic Strontium Therapy Strontium-89 4.0 mCi
Therapeutic Samarium (Quadramet) Tx Samarium-153 Lexidronam 1.0 mCi/kg      
Therapeutic P-32 Therapy P-32 (Sodium Phosphate) 2.3 mCi / sq m max 7.0 mCi
Therapeutic I-131 Rx R I-131 Capsules or Oral Solution   5-200 mCi    
Tumor Whole Body Tc-99m Sestamibi 0.314 mCi/kg 22 mCi
Tumor Whole Body Ga-67 Gallium Citrate 0.143 mCi/kg 10 mCi 1 mCi  
Tumor Whole Body Tl-201 Thallium 0.057 mCi/kg 4 mCi
Tumor Whole Body In-111 Octreotide 0.085 mCi/kg 6 mCi    
Tumor Whole Body In-111 Oncoscint 0.071 mCi/kg 5 mCi
Tumor Whole Body I-131 MIBG 0.007 mCi/kg 0.500 mCi 0.100 mCi  
Tumor Whole Body Tc-99m Arcitumomab (CEA-Scan) 0.429 mCi/kg 30.0 mCi
Tumor Prostascint Scan In-111 Capromab Pendetide   5.0 mCi    
Tumor Lymph drain (melanoma) Tc-99m Sulfur Colloid (Filtered) 0.500 mCi
Tumor Lymphatic flow (lymphadema) Tc-99m Sulfur Colloid (Filtered)   0.500 mCi / extremity    
Tumor Breast Imaging( 2 day) Tc-99m Sulfur Colloid (Unfiltered) 2.0 mCi
Tumor Breast Imaging (1 day) Tc-99m Sulfur Colloid (Unfiltered)   1.0 mCi    
Venography Lower Extremity Tc-99m MAA (dorsum injection) 0.500 mCi / foot
Venography Upper Extremity Tc-99m DTPA   0.500 mCi / hand    
PET WHOLE BODY Whole Body 18-F FDG 0.21 mCi/kg 15 mCi
PET WHOLE BODY Whole Body 18-F DOPA 0.21 mCi/kg 15 mCi    
PET NEURO Standard Brain (3D) 18-F FDG 0.14 mCi/kg 10 mCi
PET NEURO Parkinsons Dx 18-F DOPA 0.14 mCi/kg 10 mCi    
PET NEURO Brain Tumor 18-F DOPA 0.07 mCi/kg 3.5 mCi
PET NEURO Brain Flow (3D) 15-O H2O (see attending) 30 mCi    
PET NEURO Oxygen Extraction 15-O O2 (see attending) 30 mCi
PET CARDIAC Cardiac Flow (Rest and Stress) 13-N NH3 0.30 mCi/kg 30 mCi    
PET CARDIAC Cardiac Viability 18-F FDG 0.14 mCi/kg 10 mCi
Pharmacological Drugs Cardiovascular Adenosine IV 0.140 mg/kg/min x 4 min      
Pharmacological Drugs Cardiovascular Persantine (Dypridinole) IV 0.56 mg/kg x 4min
Pharmacological Drugs Cardiovascular Dobutamine 250 mg infused per protocol      
Pharmacological Drugs Gastrointestinal CCK (cholecystokinin/Kinevac) IV 0.02 ug/kg
Pharmacological Drugs Gastrointestinal Morphine IV 0.04 mg/kg      
Pharmacological Drugs Renal Captopril (Capoten) PO 25-50 mg
Pharmacological Drugs Renal Lasix (furosimide) IV 0.3-0.5 mg/kg      
Pharmacological Drugs I-131 Therapeutic Compazine PO 10 mg/ tablet